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Estradiol Test: What It Shows and What It Does Not


Quick answer: Estradiol is the main form of estrogen. An estradiol test shows how much estrogen is in your blood at one point in time. Levels rise and fall through the menstrual cycle and are lower after menopause.

About this test

The test measures estradiol (E2), the strongest and most active estrogen during the reproductive years.

Why is it ordered?

  • Irregular or missed periods.
  • Looking at menopause or perimenopause symptoms.
  • Fertility questions.
  • Following hormone treatment.

What results may show

  • Lower levels can go along with menopause, ovarian conditions or pituitary problems.
  • Higher levels can go along with ovarian conditions, pregnancy or hormone treatment.

What this test may not show

  • Levels change through the cycle, so one result is a snapshot.
  • It cannot diagnose menopause on its own.
  • Birth control, hormone therapy and some medicines change results.
  • It is usually read together with FSH and LH.

How to prepare

  • Timing in your cycle may matter. Your provider may ask for a specific day.
  • Tell your provider about hormonal birth control, hormone therapy and other medicines.

Where you can get this test

Option Price Includes
Female Hormone Panel $189 FSH, LH, estradiol, progesterone, prolactin, TSH, testosterone
Menopause Panel $149 FSH, LH, TSH, progesterone, estradiol

A doctor’s visit is not required to order. Order online, then visit our Buffalo Grove or Lake Zurich location for the sample. Review results with your own healthcare provider.

Related tests

Frequently asked questions

Why does estradiol change through the month?

The ovaries make different amounts at different stages of the cycle.

Can estradiol diagnose menopause?

Not alone. It is read with FSH, LH, your symptoms and your periods.

Does birth control affect the result?

Yes. Tell your provider what you take.

Sources

  1. MedlinePlus, National Library of Medicine. Estrogen levels test.

Medically reviewed by Rodion Levin, FNP-C, Founder and Medical Director. This page is for general education. It does not diagnose a condition or replace advice from your healthcare provider.