Thyroglobulin Antibodies Test: What It Shows and What It Does Not
Quick answer: A thyroglobulin antibody test looks for antibodies against thyroglobulin, a protein the thyroid uses to make hormone. It is read with TPO antibodies and thyroid function tests when autoimmune thyroid disease is suspected.
About this test
Thyroglobulin is a protein made in the thyroid. Thyroglobulin antibodies are immune proteins that target it.
Why is it ordered?
- Looking at the cause of an abnormal thyroid test.
- Evaluating possible Hashimoto disease or Graves disease.
- Interpreting thyroglobulin results in people followed after thyroid cancer treatment.
What results may show
- A positive result suggests an immune response aimed at the thyroid.
- It can add information when TPO antibodies are negative.
What this test may not show
- Antibodies can be present with normal thyroid function.
- It does not show how well the thyroid is working.
- A positive result alone is not a diagnosis.
- A negative result does not completely rule out autoimmune thyroid disease.
How to prepare
- No special preparation is usually needed.
- Tell your provider about thyroid medicine and supplements.
Where you can get this test
| Option | Price | Includes |
|---|---|---|
| Comprehensive Thyroid Panel | $119 | TSH, free T4, free T3, TPO antibodies, thyroglobulin antibodies |
A doctor’s visit is not required to order. Order online, then visit our Buffalo Grove or Lake Zurich location for the sample. Review results with your own healthcare provider.
Related tests
Frequently asked questions
When is this test used?
When autoimmune thyroid disease is suspected, usually along with TPO antibodies.
Does a positive result mean I need treatment?
Not by itself. Your provider reads it with TSH, free T4 and your symptoms.
Is this a thyroid cancer test?
No. It is an antibody test. In people followed after thyroid cancer, it helps interpret a different test.
Sources
Medically reviewed by Rodion Levin, FNP-C, Founder and Medical Director. This page is for general education. It does not diagnose a condition or replace advice from your healthcare provider.
