Syphilis Test: What It Shows and What It Does Not
Quick answer: A syphilis blood test looks for antibodies your body makes in response to the bacteria that cause syphilis. A positive screening test is confirmed with a second test.
About this test
The blood test looks for antibodies to Treponema pallidum or markers of the infection. Syphilis testing often uses two steps to confirm a result.
Why is it ordered?
- Routine screening for sexually active people.
- A new partner or a partner who tested positive.
- A sore or rash that may be syphilis.
What results may show
- A positive result suggests current or past syphilis and needs confirmation and follow up.
- A negative result after the window period makes infection unlikely.
What this test may not show
- A very recent infection may not show yet because antibodies take weeks to appear.
- Some tests stay positive after successful treatment.
- It does not show the stage of infection by itself.
- A positive result needs a provider visit.
How to prepare
- No special preparation is needed.
Where you can get this test
| Option | Price | Includes |
|---|---|---|
| STD Screening Panel, Basic | $129 | Chlamydia, gonorrhea, syphilis, HIV 1 and 2 |
| STD Screening Panel, Comprehensive | $199 | Chlamydia, gonorrhea, trichomoniasis, syphilis, HIV 1 and 2, hepatitis B surface antigen, hepatitis C antibody |
A doctor’s visit is not required to order. Order online, then visit our Buffalo Grove or Lake Zurich location for the sample. Review results with your own healthcare provider.
Related tests
Frequently asked questions
How long after exposure does the test turn positive?
Antibodies can take a few weeks to appear. Your provider can advise on repeat testing.
Can the test stay positive after treatment?
Yes. Some antibody tests remain positive for life.
What happens after a positive screening test?
A confirmatory test and a visit with a provider.
Sources
Medically reviewed by Rodion Levin, FNP-C, Founder and Medical Director. This page is for general education. It does not diagnose a condition or replace advice from your healthcare provider.
